USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: PHP14_HUMAN USC-OGP 2-DE database:  PHP14_HUMAN PHP14_HUMAN General information about the entry View entry in simple text format Entry name PHP14_HUMAN Primary accession number Q9NRX4 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=14 kDa phosphohistidine phosphatase {ECO:0000303|PubMed:12383260}; EC=3.9.1.3 {ECO:0000269|PubMed:19836471, ECO:0000269|PubMed:25574816}; AltName: Full=Phosphohistidine phosphatase 1 {ECO:0000303|PubMed:25574816}; Short=PHPT1 {ECO:0000303|PubMed:25574816}; AltName: Full=Protein histidine phosphatase {ECO:0000303|PubMed:19836471}; Short=PHP {ECO:0000303|PubMed:19836471}; AltName: Full=Protein janus-A homolog;. Gene name Name=PHPT1 Synonyms=PHP14 ORFNames=CGI-202, HSPC141 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1342: pI=5.48; Mw=15156 Cross-references UniProtKB/Swiss-Prot Q9NRX4; PHP14_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PHP14_HUMAN Primary accession number Q9NRX4 Secondary accession number(s) B1AMX0 B1AMX1 Q9H0Y3 Sequence was last modified on  October 1, 2000 (version 1) Annotations were last modified on  March 15, 2017 (version 144) Name and origin of the protein Description RecName: Full=14 kDa phosphohistidine phosphatase {ECO:0000303|PubMed:12383260}; EC=3.9.1.3 {ECO:0000269|PubMed:19836471, ECO:0000269|PubMed:25574816}; AltName: Full=Phosphohistidine phosphatase 1 {ECO:0000303|PubMed:25574816}; Short=PHPT1 {ECO:0000303|PubMed:25574816}; AltName: Full=Protein histidine phosphatase {ECO:0000303|PubMed:19836471}; Short=PHP {ECO:0000303|PubMed:19836471}; AltName: Full=Protein janus-A homolog; Gene name Name=PHPT1 Synonyms=PHP14 ORFNames=CGI-202, HSPC141 Encoded on Name=PHPT1; Synonyms=PHP14; ORFNames=CGI-202, HSPC141 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Protein phosphatase; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF393504; AAN52504.1; -; mRNA EMBL AF164795; AAF80759.1; -; mRNA EMBL AF285119; AAG01156.1; -; mRNA EMBL AL136644; CAB66579.1; -; mRNA EMBL AL355987; CAI12692.1; -; Genomic_DNA EMBL AL355987; CAI12693.1; -; Genomic_DNA EMBL CH471090; EAW88289.1; -; Genomic_DNA EMBL BC024648; AAH24648.1; -; mRNA EMBL BQ922335; -; NOT_ANNOTATED_CDS; mRNA CCDS CCDS48060.1; -. [Q9NRX4-2]; . CCDS CCDS7009.1; -. [Q9NRX4-1]; . RefSeq NP_001129333.1; NM_001135861.2. [Q9NRX4-2]; . RefSeq NP_054891.2; NM_014172.5. [Q9NRX4-1]; . UniGene Hs.409834; -; . UniGene Hs.731711; -; . PDB 2AI6; NMR; -; A=1-125 PDB 2HW4; X-ray; 1.90 A; A=5-125 PDB 2NMM; X-ray; 2.70 A; A/B/C=1-125 PDB 2OZW; NMR; -; A=1-125 PDB 2OZX; NMR; -; A=1-125 PDBsum 2AI6; -; . PDBsum 2HW4; -; . PDBsum 2NMM; -; . PDBsum 2OZW; -; . PDBsum 2OZX; -; . ProteinModelPortal Q9NRX4; -; . SMR Q9NRX4; -; . BioGrid 118854; 19; . DIP DIP-48597N; -; . IntAct Q9NRX4; 3; . MINT MINT-1394164; -; . STRING 9606.ENSP00000247665; -; . DEPOD Q9NRX4; -; . iPTMnet Q9NRX4; -; . PhosphoSitePlus Q9NRX4; -; . DMDM 25008934; -; . EPD Q9NRX4; -; . PaxDb Q9NRX4; -; . PeptideAtlas Q9NRX4; -; . PRIDE Q9NRX4; -; . TopDownProteomics Q9NRX4-1; -. [Q9NRX4-1]; . DNASU 29085; -; . Ensembl ENST00000247665; ENSP00000247665; ENSG00000054148. [Q9NRX4-1]; . Ensembl ENST00000371661; ENSP00000360724; ENSG00000054148. [Q9NRX4-2]; . GeneID 29085; -; . KEGG hsa:29085; -; . UCSC uc064xew.1; human. [Q9NRX4-1]; . CTD 29085; -; . DisGeNET 29085; -; . GeneCards PHPT1; -; . HGNC HGNC:30033; PHPT1; . HPA CAB013584; -; . HPA HPA020952; -; . MIM 610167; gene; . neXtProt NX_Q9NRX4; -; . OpenTargets ENSG00000054148; -; . PharmGKB PA134948141; -; . eggNOG ENOG410IZ5G; Eukaryota; . eggNOG ENOG4111SA6; LUCA; . GeneTree ENSGT00390000002738; -; . HOGENOM HOG000231559; -; . HOVERGEN HBG053589; -; . InParanoid Q9NRX4; -; . KO K01112; -; . OMA GWAEYHA; -; . OrthoDB EOG091G10Y7; -; . PhylomeDB Q9NRX4; -; . TreeFam TF315158; -; . BioCyc MetaCyc:ENSG00000054148-MONOMER; -; . ChiTaRS PHPT1; human; . EvolutionaryTrace Q9NRX4; -; . GeneWiki PHPT1; -; . GenomeRNAi 29085; -; . PRO PR:Q9NRX4; -; . Proteomes UP000005640; Chromosome 9; . Bgee ENSG00000054148; -; . CleanEx HS_PHPT1; -; . ExpressionAtlas Q9NRX4; baseline and differential; . Genevisible Q9NRX4; HS; . GO GO:0005829; C:cytosol; IDA:BHF-UCL; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0019855; F:calcium channel inhibitor activity; IDA:BHF-UCL; . GO GO:0044325; F:ion channel binding; IPI:BHF-UCL; . GO GO:0008969; F:phosphohistidine phosphatase activity; IDA:BHF-UCL; . GO GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW; . GO GO:2000984; P:negative regulation of ATP citrate synthase activity; IDA:BHF-UCL; . GO GO:0051350; P:negative regulation of lyase activity; IDA:BHF-UCL; . GO GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:BHF-UCL; . GO GO:0035971; P:peptidyl-histidine dephosphorylation; IDA:BHF-UCL; . GO GO:2000147; P:positive regulation of cell motility; IMP:BHF-UCL; . GO GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl; . GO GO:0006470; P:protein dephosphorylation; IDA:BHF-UCL; . GO GO:2000249; P:regulation of actin cytoskeleton reorganization; IMP:BHF-UCL; . InterPro IPR007702; Janus; . InterPro IPR028441; PHPT1; . PANTHER PTHR12258; PTHR12258; 1; . PANTHER PTHR12258:SF15; PTHR12258:SF15; 1; . Pfam PF05005; Ocnus; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]